DECIPHERING THE MECHANOBIOLOGICAL AND IMMUNOLOGICAL PATHWAYS OF BIOPROSTHETIC HEART VALVE CALCIFICATION: THE DAWN OF NEXT GENERATION SMART BIO SCAFFOLDS

Authors

  • Kakhorova Karomatkhon Sovronbayevna Lecture of General Medical sciences of Medical Faculty NamSU Author
  • Kurbonova Madinabonu Shukhrat kizi 1st year student of Medical Faculty NamSU Author
  • Jurayeva Mukhtasar Ilyosovna 1st year student of Medical Faculty NamSU Author

Keywords:

This review provides a comprehensive, molecular-biomedical synthesis

Abstract

Bioprosthetic heart valves (BHVs) remain the gold standard for valvular replacement; however, their clinical longevity is strictly compromised by structural valve degeneration (SVD), primarily driven by accelerated calcification. While mechanical stresses are recognized, the orchestrating molecular cascades and the specific cellular cross-talk at the graft-host interface remain fully elucidated

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Published

2026-06-04

Issue

Vol. 4 No. 06 (2026): WEJMMS

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

DECIPHERING THE MECHANOBIOLOGICAL AND IMMUNOLOGICAL PATHWAYS OF BIOPROSTHETIC HEART VALVE CALCIFICATION: THE DAWN OF NEXT GENERATION SMART BIO SCAFFOLDS. (2026). Western European Journal of Medicine and Medical Science, 4(06), 1-6. https://westerneuropeanstudies.com/index.php/3/article/view/3699

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